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Conoidin A

CAS No. 18080-67-6

Conoidin A ( —— )

产品货号. M23821 CAS No. 18080-67-6

Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
25MG ¥348 有现货
50MG ¥494 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Conoidin A
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties.
  • 产品描述
    Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. It covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 μM. It also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII). Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease.
  • 同义词
    ——
  • 通路
    Microbiology/Virology
  • 靶点
    Parasite
  • 受体
    Parasite
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    18080-67-6
  • 分子量
    348.0
  • 分子式
    C10H8Br2N2O2
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:14.29 mg/mL?(41.06 mM;?Need ultrasonic)
  • SMILES
    [O-][N+]1=C(CBr)C(CBr)=[N+]([O-])C2=CC=CC=C21
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Gu Liu, et al. Optimisation of conoidin A, a peroxiredoxin inhibitor. ChemMedChem. 2010 Jan;5(1):41-5.
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